Results 61 to 70 of about 577,665 (343)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Challenges in cross-cultural/multilingual music information seeking
, 2005 Understanding and meeting the needs of a broad range of music users across different cultures and languages are central in designing a global music digital library.
Lee, Jin Ha +5 more
core +1 more source
Perilaku Pencarian Informasi Pemustaka Dinas Perpustakaan dan Arsip Kabupaten Tangerang
Buletin Al-Turas, 2018 This article is intended to investigate the users’ information seeking behaviour in Dinas Perpustakaan dan Arsip (Perpusip) Kabupaten Tangerang, based on Seven Pillars model. Data are collected by using questionnaire and observation.
Nurul Hayati, Diaz Mawar Sawitri
doaj +1 more source
The information needs and information seeking behaviour of family doctors [PDF]
Health Information & Libraries Journal, 2004 AbstractAims: To explore the information needs and information seeking behaviour of family doctors, identifying any differences in attitudes and behaviours deriving from membership of a training practice and investigating the impact of a practice librarian.Methods: A case study of general practitioners (GPs) in Aylesbury Vale incorporated a ...
openaire +2 more sources
Public Transport, 2019 This paper investigates factors influencing public transport passengers’ pre-travel information-seeking behaviours in a British urban environment.
Godwin Yeboah +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Information behaviour of university students [PDF]
, 2009 This work presents the preliminary results of an information behaviour study of students in two Spanish universities. A qualitative methodology was adopted and the results analysed following the grounded theory.
González-Teruel, Aurora +2 more
core
Information Research: An International Electronic Journal, 2005 [Introduction. We explored Harris and Dewdney's principle that people follow habitual patterns when seeking everyday information along with Pettigrew's notion of information grounds. [Method.
Fisher Naumer +3 more
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Patient information needs: pre- and post-consultation. [PDF]
, 2006 This paper presents findings from a study of information seeking behaviour by National Health Service patients which explored motivational triggers for infor- mation needs. Previous research has highlighted the importance of contextual elements in users'
Blandford, Ann +5 more
core +1 more source