Results 141 to 150 of about 2,005,614 (317)

Department of Corporate and Information Services annual report 2004-2005 [PDF]

open access: yes, 2005
Made available by the Library & Archives NT via the Publications (Legal Deposit) Act 2004 (NT)

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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Department of Corporate and Information Services annual report 2006 - 2007 [PDF]

open access: yes, 2007
Made available by the Library & Archives NT via the Publications (Legal Deposit) Act 2004 (NT)

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Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Department of Corporate and Information Services annual report 2012 -2013 [PDF]

open access: yes, 2013
Made available by the Library & Archives NT via the Publications (Legal Deposit) Act 2004 (NT)

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Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The Critical Need to Build a European Governance Model for Online Access to Medical Information Services: A Position Paper. [PDF]

open access: yesPharmaceut Med, 2021
Pienaar S   +6 more
europepmc   +1 more source

Department of Corporate and Information Services annual report 2007 - 2008 [PDF]

open access: yes, 2008
Made available by the Library & Archives NT via the Publications (Legal Deposit) Act 2004 (NT)

core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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