Results 61 to 70 of about 993,913 (308)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Industry and Public Sector Cooperation for Information Sharing: Ports of the Puget Sound [PDF]

open access: yes, 2009
This report presents the findings of the Maritime Information Sharing Taskforce (MIST) research effort for the Washington State Puget Sound ports. Using a participatory design approach, the researchers partnered with federal and commercial stakeholders ...
Englehorn, Lyla   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Homeostasis imbalance process ontology: a study on COVID-19 infectious processes

open access: yesBMC Medical Informatics and Decision Making
Background One significant challenge in addressing the coronavirus disease 2019 (COVID-19) pandemic is to grasp a comprehensive picture of its infectious mechanisms.
Yuki Yamagata   +3 more
doaj   +1 more source

High-Resolution Daily Evapotranspiration Estimation in Arid Agricultural Regions Based on Remote Sensing via an Improved PT-JPL and CUWFM Fusion Framework

open access: yesRemote Sensing
Evapotranspiration (ET) plays a crucial role in the terrestrial water cycle, especially in arid and semi-arid agricultural regions where precise water management is essential.
Hongwei Liu   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Cross-modal feature interaction network for heterogeneous change detection

open access: yesGeo-spatial Information Science
Heterogeneous change detection is a task of considerable practical importance and significant challenge in remote sensing. Heterogeneous change detection involves identifying change areas using remote sensing images obtained from different sensors or ...
Zhiwei Yang   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

National-scale 10-m maps of cropland use intensity in China during 2018–2023

open access: yesScientific Data
The amount of actively cultivated land in China is increasingly threatened by rapid urbanization and rural population aging. Quantifying the extent and changes of active cropland and cropping intensity is crucial to global food security.
Bingwen Qiu   +11 more
doaj   +1 more source

Tree-Based and Optimum Cut-Based Origin-Destination Flow Clustering

open access: yesISPRS International Journal of Geo-Information, 2019
Data about the movements of diverse objects, including human beings, animals, and commodities, are collected in growing amounts as location-aware technologies become pervasive. Clustering has become an increasingly important analytical tool for revealing
Qiuliang Xiang, Qunyong Wu
doaj   +1 more source

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