Results 101 to 110 of about 2,772,234 (308)
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Statistical Computing in Information Society
In the presence of massive data coming with high heterogeneity we need to change our statistical thinking and statistical education in order to adapt both - classical statistics and software developments that address new challenges.
Domański Czesław, Jędrzejczak Alina
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Information society before information society
The discourse on “the information society” developed until the 70’s as one of the prevailing discourse in our society; with promises to link information technology and free market with economic growth and human progress. This eventually became something like the official ideology of the European Union as demonstrated by the famous Lisbon strategy to ...
openaire +1 more source
Volume 21 - 1990: GEOLOGICAL SOCIETIES AND INFORMATION TRANSFER IN THE ELECTRONIC AGE - Proceedings of the 25th Meeting of the Geoscience Information Society (25th Anniversary 1965-1990) [PDF]
Proceedings of the 25th Meeting of the Geoscience Information Society held October 29 - November 1, 1990 in Dallas, Texas (25th Anniversary 1965 ...
Geoscience Information Society
core
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Volume 15 - 1984: MAPS IN THE GEOSCIENCE COMMUNITY - Proceedings of the 19th Meeting of the Geoscience Information Society [PDF]
Proceedings of the 19th Meeting of the Geoscience Information Society held November 5-8, 1984 in Reno ...
Geoscience Information Society
core
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source

