Results 101 to 110 of about 4,309,068 (299)

Status of Information Technology Services Management in Libraries and Special Information Centers in Metro Tehran [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2011
Objectives: The present study investigates the state of administration of information technology services in libraries and special information centers in metropolitan Tehran Methodology: A quantitative approach was used using literature survey.
Z Abolghassemi   +2 more
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Patent portfolio analysis model based on legal status information

open access: yes, 2014
Purpose: This research proposes a patent portfolio analysis model based on the legal status information to chart out a competitive landscape in a particular field, enabling organizations to position themselves within the overall technology landscape.
WANG Xuezhao   +4 more
core  

Current Status and Associated Factors of Health Information Literacy Among the Community Elderly in Central China in the COVID-19 Pandemic: A Cross-Sectional Study

open access: yesRisk Management and Healthcare Policy, 2022
Pan Li,1,2 Jiaming Zhong,3 Huiqiong Chen,1 Ting Qin,1 Lingyao Meng2 1School of Nursing, Xiangnan University, Chenzhou, 423000, People’s Republic of China; 2College of Nursing and Allied Health Sciences, St.
Li P, Zhong J, Chen H, Qin T, Meng L
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Status of Libraries and Information Centres in Namibia

open access: yesБиблиосфера
In an increasingly interconnected world, understanding of cultures, traditions and systems of different countries is of growing importance. This article aims to acquaint readers of this journal with library systems in Namibia, shedding more light on its ...
S. Negumbo
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Understanding patrons' Micro-Level Information Seeking (MLIS) in Information Retrieval Situations.

open access: yes, 2010
[[abstract]]Elicitation is a communicative act to request information during a dialogue, which reflects the questioner's problems at hand, perplexity, interests, or perhaps internal concerns, either voluntarily or unintentionally.
Wu, Mei-Mei, 吳美美
core  

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