Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Status of Information Technology Services Management in Libraries and Special Information Centers in Metro Tehran [PDF]
Objectives: The present study investigates the state of administration of information technology services in libraries and special information centers in metropolitan Tehran Methodology: A quantitative approach was used using literature survey.
Z Abolghassemi +2 more
doaj
Inconsistencies in Reported Employment Characteristics among Employed Stayers [PDF]
The paper deals with measurement error, and its potentially distorting role, in information on industry and professional status collected by labour force surveys.
Bassi, Francesca +2 more
core
Equality - Focus on Sport, Football and Inclusivity [PDF]
This edition contains features on: • LimbPower – new status as a National Disability Sports Organisation • Football and inclusivity - Dr Dan Parnell • Games Starters volunteering opportunity at the Cerebral Palsy International Sports and Recreation ...
Parnell, D
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Plant breeding for organic farming: current status and problems in Europe [PDF]
Compendium is a part of Deliverable 4 of 6th FP SSA project “Environmental friendly food production system: requirements for plant breeding and seed production” (ENVIRFOOD) and contains information about current status and problems in EU regarding to ...
Legzdina, Linda, Skrabule, Ilze
core
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Pan Li,1,2 Jiaming Zhong,3 Huiqiong Chen,1 Ting Qin,1 Lingyao Meng2 1School of Nursing, Xiangnan University, Chenzhou, 423000, People’s Republic of China; 2College of Nursing and Allied Health Sciences, St.
Li P, Zhong J, Chen H, Qin T, Meng L
doaj
FY 1996 Juvenile Justice and Delinquency Prevention Act Compliance Monitoring Report [PDF]
The Juvenile Justice and Delinquency Prevention Act (JJDPA) mandates removal of status offenders and nonoffenders from secure detention and correctional facilities, sight and sound separation of juveniles and adults, and removal of juveniles from adult ...
Atwell, Cassie +2 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

