Results 91 to 100 of about 2,677,577 (337)
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Recent advances on information transmission and storage assisted by noise
, 2013 The interplay between nonlinear dynamic systems and noise has proved to be of great relevance in several application areas. In this presentation, we focus on the areas of information transmission and storage.
A Dari +43 more
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Enhancement of spin orbit torques in a Tb-Co alloy magnetic wire by controlling its Tb composition
AIP Advances, 2017 We investigated the current-induced domain wall motion (CIDWM) in Pt(3 nm)/TbxCo1-x(6 nm) alloy wires with various Tb composition (x). We found that the threshold current density (Jth) for the CIDWM in the TbxCo1-x alloy wires decreases with increasing x.
Yuichiro Kurokawa +2 more
doaj +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Optical information storage [PDF]
, 1984 An optical disc including a medium having both a continuous phase and a non-continuous phase yields excellent contrast and stability for optical recording purposes.
Blonder, Greg, Hebard, Arthur
core
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Optimization of information storage systems
Information and Control, 1968 In this paper the writers have developed a model and an optimization technique for the design of hierarchical structures of memory so as to minimize the average access time to blocks of information stored in the hierarchy for a given cost constraint. The assumption is made that the “activity profile” giving the relative frequencies with which blocks ...
C.V. Ramamoorthy, K.M. Chandy
openaire +2 more sources
Replica Selection in the Globus Data Grid [PDF]
, 2000 The Globus Data Grid architecture provides a scalable infrastructure for the management of storage resources and data that are distributed across Grid environments. These services are designed to support a variety of scientific applications, ranging from
Foster, Ian +2 more
core +4 more sources
, 2015 Privacy of the outsourced data is one of the major challenge.Insecurity of the network environment and untrustworthiness of the service providers are obstacles of making the database as a service.Collection and storage of personally identifiable ...
Binu, V. P. +2 more
core +1 more source