Results 61 to 70 of about 940,318 (334)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Suppressing Structural Relaxation in Nanoscale Antimony to Enable Ultralow‐Drift Phase‐Change Memory Applications

open access: yesAdvanced Science, 2023
Phase‐change random‐access memory (PCRAM) devices suffer from pronounced resistance drift originating from considerable structural relaxation of phase‐change materials (PCMs), which hinders current developments of high‐capacity memory and high ...
Bin Chen   +8 more
doaj   +1 more source

Write-Optimized and Consistent Skiplists for Non-Volatile Memory

open access: yesIEEE Access, 2021
Skiplist as an in-memory index performs pretty well on rapid insertions because there are no rotations or reallocations for rebalancing. The emerging non-volatile memory (NVM) technologies have spurred a deep interest in designing efficient NVM-based ...
Renzhi Xiao   +6 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Minimization of Storage Cost in Distributed Storage Systems with Repair Consideration [PDF]

open access: yesarXiv, 2011
In a distributed storage system, the storage costs of different storage nodes, in general, can be different. How to store a file in a given set of storage nodes so as to minimize the total storage cost is investigated. By analyzing the min-cut constraints of the information flow graph, the feasible region of the storage capacities of the nodes can be ...
arxiv  

Cold Storage Information System

open access: yes, 2017
To develop a part of the new web based inventory management system replacing the old pen and paper based record system of the large chain of cold storage present in the state of West Bengal ...
openaire   +3 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Natural Data Storage: A Review on sending Information from now to then via Nature [PDF]

open access: yesarXiv, 2015
Digital data explosion drives a demand for robust and reliable data storage medium. Development of better digital storage device to accumulate Zetta bytes (1 ZB = $10^{21}$ bytes ) of data that will be generated in near future is a big challenge. Looking at limitations of present day digital storage devices, it will soon be a big challenge for data ...
arxiv  

Error Correction for DNA Storage [PDF]

open access: yesarXiv, 2023
DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting coding theoretic challenges, some of which are new.
arxiv  

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