Results 41 to 50 of about 611 (210)

High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography

Nature Communications
DNA origami information storage is a promising alternative to silicon-based data storage, offering a molecular cryptography technique concealing information within DNA origami.
Gde Bimananda Mahardika Wisna, Daria Sukhareva, Jonathan Zhao, Prathamesh Chopade, Deeksha Satyabola, Michael Matthies, Subhajit Roy, Chao Wang, Petr Šulc, Hao Yan, Rizal F. Hariadi   +10 more
doaj   +1 more source

Availability and coverage of hydrologic data in the US geological survey National Water Information System (NWIS) and US Environmental Protection Agency Storage and Retrieval System (STORET) [PDF]

Earth Science Informatics, 2008
The need for a unified and improved data access system for the nation’s vast hydrologic data holdings has increased over the past few years as researchers strive for better understanding the human impact on the nation’s water cycle. Large mission oriented data repositories such as the USGS’ National Water Information System (NWIS) and EPA’s Storage and
Bora Beran, Michael Piasecki
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Text-Enhanced Graph Attention Hashing for Cross-Modal Retrieval

Entropy
Deep hashing technology, known for its low-cost storage and rapid retrieval, has become a focal point in cross-modal retrieval research as multimodal data continue to grow.
Qiang Zou, Shuli Cheng, Anyu Du, Jiayi Chen   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Distributed processing practice of the massive GIS data based on HBase

大数据, 2016
Based on the distributed database HBase,a kind of GIS data management system was designed.The system optimized the generated and stored procedures of raster data,which could be directly written into the storage and indexing of the HBase.At the same time ...
Xuemei LI, Junfeng XING, IUDawei L, Haiyang WANG, Wei LIU   +4 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Retrieval algorithm based on locally sensitive hash for ocean observation data

Frontiers in Marine Science
As an important technology for eliminating redundant data, data deduplication significantly impacts today’s era of explosive data growth. In recent years, due to the rapid development of a series of related industries, such as ocean observation, ocean ...
Meijuan Jia, Xiaodong Mao, Shuai Guo, Xin Li   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source