Results 131 to 140 of about 15,321,837 (291)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Enhancing Students’ Knowledge-Based Economy Skills at Sultan Qaboos University

Education Sciences
This study examines the readiness of Sultan Qaboos University (SQU) students for the knowledge-based economy, focusing on their awareness, perceptions, and skills.
Nour Eldin Elshaiekh, Ahmed Shehata, Noura Al Hosni   +2 more
doaj   +1 more source

A guide to nestling development and aging in altricial passerines [PDF]

, 2007
Nestling growth and development studies have been a topic of interest for a greater part of the last century (Sutton 1935, Walkinshaw 1948) and continue to be of interest today. This is not surprising since studies on nestling growth can provide a wealth
Gardali, Thomas, Geupel, Geoffrey R., Gouse, Paula J., Jones, Stephanie L., Jongsomjit, Dennis   +4 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Alcohol, assault and licensed premises in inner-city areas [PDF]

, 2013
This report contains eight linked feasibility studies conducted in Cairns during 2010. These exploratory studies examine the complex challenges of compiling and sharing information about incidents of person-to-person violence in a late night ...
Alan R. Clough, Charmaine S. Hayes-Jonkers, Edward S. Pointing   +2 more
core  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

(Un)conventional ways of dialogic information retrieval using prompt engineering and the role of AI literacy

Information Research: An International Electronic Journal
Introduction. This study examines students’ use of ChatGPT for information retrieval and creative tasks, integrating AI literacy into library and information science (LIS) models and addressing gaps in AI-mediated processes and ethics. Method.
Monika Krakowska, Magdalena Zych
doaj   +1 more source

Studying temporal information processing

Acoustical Science and Technology, 2012
Que´bec is the only one of ten provinces in Canada to bepredominantly French. Laval University is located in thesecond largest city of this province, Que´bec city. This cityis more than 400 years old, which is quite old for a NorthAmerican city. About half a million people live in Que´bec,a city that is offering a variety of fine cultural activities ...
openaire   +2 more sources