Results 61 to 70 of about 15,491,831 (293)

Analyzing genome-wide association studies with an FDR controlling modification of the Bayesian information criterion

open access: yes, 2014
The prevailing method of analyzing GWAS data is still to test each marker individually, although from a statistical point of view it is quite obvious that in case of complex traits such single marker tests are not ideal.
Bodenstorfer, Bernhard   +2 more
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

On the Reuse of Scientific Data

open access: yesData Science Journal, 2017
While science policy promotes data sharing and open data, these are not ends in themselves. Arguments for data sharing are to reproduce research, to make public assets available to the public, to leverage investments in research, and to advance research ...
Irene V. Pasquetto   +2 more
doaj   +1 more source

Cultural issues, organisational hierarchy and information fulfilment: an exploration of relationships [PDF]

open access: yes, 2007
Purpose – The purpose of this paper is to present the cultural results of a three year study into the concept of information fulfilment and considers the impact of culture on levels of information fulfilment.
Burke, ME
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Modeling and Evaluation of the Possibilities of Forming a Regional Industrial Symbiosis Networks

open access: yesSocial Sciences, 2018
Industrial symbiosis (IS) is a term used to describe a network of diverse organizations that make use of different byproducts to improve their ability to achieve common goals, improve environmental conditions, and/or improve business and technical ...
Biljana Mileva-Boshkoska   +2 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Discover the Thracians – An Approach for Use of 2D and 3D Technologies for Digitization of Cultural Heritage in the Field of Elearning

open access: yesDigital Presentation and Preservation of Cultural and Scientific Heritage, 2012
Information and communication technologies (ICT) offer an easier access to and a multiperspective view of cultural heritage artifacts and may also enrich and improve cultural heritage education through the adoption of innovative learning/teaching methods.
Oleg Konstantinov   +3 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

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