Results 221 to 230 of about 15,663,128 (307)

Identifying drivers of dengue fever outbreaks in Mauritius using Geographic Information System. [PDF]

Jamba
Goorah S, Nowbuth M, Gooroochurn M.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Enhancing the antenatal care quality through incentivized routine health information system in Northwestern Ethiopia: a quasi-experimental study (2020-2021). [PDF]

BMC Public Health
Taye BK, Gezie LD, Atnafu A, Mengiste SA, Kaasbøll JJ, Gullslett MK, Tilahun B.   +6 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Impact of Health Information System Interventions on Maternal Health Service Utilization in Oromia and Gambella Regions, Ethiopia: A Comparative Cross-Sectional Study. [PDF]

Digit Health
Abadula KH, Worku AG, Debelew GT, Wordofa MA.   +3 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Geospatial Visualization of Dialysis Accessibility in Shiraz: A Nonanalytical Geographic Information System Approach. [PDF]

Health Sci Rep
Ghahramani P, Kiani B, Norouzkhani N, Khoshkangin A, Kheirdoust A, Mazaheri Habibi MR.   +5 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Outcomes and Predictors of Recurrence and Survival in Surgically Resected Localized Chromophobe Renal Cell Carcinoma: Results from the Canadian Kidney Cancer Information System (CKCis). [PDF]

Curr Oncol
Arenovich E, Breau R, Rendon R, Mallick R, Tanguay S, Pouliot F, Lavallee L, Feifer A, Finelli A, Bansal R, Lattouf JB, Mannas M, Bhindi B, Nayak JG, Basappa N, Heng DYC, Lalani AA, Bjarnason G, Wood L.   +18 more
europepmc   +1 more source