Results 51 to 60 of about 15,399,652 (281)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

A deep learning algorithm for joint direct tracking and classification of manoeuvring sources

open access: yesIET Radar, Sonar & Navigation, 2022
The remarkable success of deep learning technologies has provided new ideas for solving complex tracking problems. It is difficult for traditional algorithms to directly estimate the trajectory vector and target class from the received signal due to the ...
Wanting Yu   +4 more
doaj   +1 more source

Study Information System Scheduling Based on Procurement of Goods in Connection with the Goods in Inventory Control PT. Usi-jaya [PDF]

open access: yes, 1990
One of the major factors that support the production is the supply of goods, inaddition to the human / labor, machinery, and capital. Duty management arranged forthe above factors can work together to produce maximum output with minimuminput. Inventories
Sadikin, M. A. (M), Wahab, S. (Sulwan)
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Raw Material Supply System Information PT. Comfort Aire Aneka Technic [PDF]

open access: yes, 2001
Raw materials inventory system at PT.Comfort Aire Aneka Technic stillmenggunakansistem manually, which causes the system procedures haveshortcomings and weaknesses that have not been able to optimize vehicle is inproviding information quickly and ...
K, M. I. (MMSI), Yatono, Y. (Yatono)
core  

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

Information System Design in the Yamaha Music School [PDF]

open access: yes, 1997
The design of Information Systems was written because this now requires speed and accuracy of the information needed by someone to assist their daily work.
Drs. H. Soetirto Sadikin, M. A. Drs. H. Soetirto Sadikin, M. A   +1 more
core  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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