Results 101 to 110 of about 1,751,226 (296)

Advantageous selection in private health insurance: The case of Australia [PDF]

open access: yes
When consumers have private information about risk of suffering a loss, or equivalently, if insurers are prohibited from using observable information on risk in underwriting, theoretical models of insurance predict adverse selection.
Elizabeth Savage   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Information System Selection

open access: yes, 2020
Master thesis deals with the analysing of the current information system and then with the alternatives and implementation of a new information system in a company. The first part of the master thesis is focused on explaining the theoretical concepts, in
Veselík, Martin
core   +1 more source

Optimal Site Selection of Health Centers Using Geographical Information System Software in Maragheh, Iran

open access: yesمدیریت اطلاعات سلامت, 2017
Introduction: Medical centers directly affect the health of the individual and the community; quick and inexpensive access to these centers is important and necessary in urban communities. Site selection of health centers is highly important such that it
Akbar Moradi, Zahra Nasiri
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Information selection and fusion in vision systems.

open access: yes, 2010
Handling the enormous amounts of data produced by data-intensive imaging systems, such as multi-camera surveillance systems and microscopes, is technically challenging. While image and video compression help to manage the data volumes, they do not address the basic problem of information overflow. In this PhD we tackle the problem in a more drastic way.
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

An intelligent radio access network selection and optimisation system in heterogeneous communication environments

open access: yes, 2010
PhDThe overlapping of the different wireless network technologies creates heterogeneous communication environments. Future mobile communication system considers the technological and operational services of heterogeneous communication environments. Based
Luo, Weizhi
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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