Results 251 to 260 of about 43,078,898 (347)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Unlocking the Mediating and Moderating Role of Information Security in Information Systems: A Combined TAM, ISM, and HBM Model

Human Behavior and Emerging Technologies
Md. Mominul Islam, Mohammad Rakibul Islam Bhuiyan, Syed Hasibul Islam, Mst. Nowshin Tabassum, Motasim Billah   +4 more
doaj   +1 more source

Can Real-World Data From Hospital Information Systems Be Directly Utilized for Efficacy Studies: An Analysis of Data Time Points. [PDF]

J Evid Based Med
Luo J, Zhang A, Gao W, Bu X, Li R, Ye Z, Zhang X, Ren L, Jiang Y, Guan Z, Guan H, Tao L, Dai G, Zhao C, Shang H.   +14 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Ranking and selecting hospital information systems: A multi-criteria decision making approach using TOPSIS in Hamadan, Iran. [PDF]

PLOS Digit Health
Bouraghi H, Mohammadpour A, Maamaki A, Karamiyan P.   +3 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Health Information Systems' Support for Management and Changing Work: Survey Study Among Physicians.

JMIR Med Inform
Heponiemi T, Virtanen L, Kainiemi E, Saukkonen P, Reponen J, Lääveri T.   +5 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

The accuracy and consistency of public health data in Brazilian information systems: identification of gaps and challenges to be faced in a municipality in the Amazon region. [PDF]

Front Public Health
Simeone D, Laranjeira A, Lopes PMR, Nogueira VCS, Sousa DS, Martins YJ, Carvalho MWA, Eyzaguirre IAL, Fernandes MEB, Oliveira-Filho AB.   +9 more
europepmc   +1 more source