Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel+9 more
wiley +1 more source
Bridging the know-do gap: improved adolescent sexual and reproductive health and health information systems in West Africa and the Middle East. [PDF]
Sinha C, Ingabire MG, Schryer-Roy AM.
europepmc +1 more source
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee+3 more
wiley +1 more source
Development and Validation of an Indicator System for Evaluating Clinical Nursing Process Quality Using Mobile Nursing Information Systems. [PDF]
Ge H, Wang Q, Liu S, Tian Y, Ma J.
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
The Challenges and Value of Using Video-Assisted Education Tools and Digital Information Systems for Post-discharge Care in Elderly Patients: A Scoping Review. [PDF]
Hassan M+5 more
europepmc +1 more source
Utilization of health management information systems for decision making among healthcare professionals in Ketu North Municipality, Ghana: a descriptive cross-sectional study. [PDF]
Zeng V+3 more
europepmc +1 more source
A Taxonomy for Health Information Systems.
Janssen A, Donnelly C, Shaw T.
europepmc +1 more source
Information systems project success surveys - Insights from the last 30 years. [PDF]
Loureiro E+3 more
europepmc +1 more source