Results 41 to 50 of about 10,401,843 (327)

CC-interop : COPAC/Clumps Continuing Technical Cooperation. Final Project Report [PDF]

, 2004
As far as is known, CC-interop was the first project of its kind anywhere in the world and still is. Its basic aim was to test the feasibility of cross-searching between physical and virtual union catalogues, using COPAC and the three functioning "clumps"
Dunsire, Gordon, Gilby, John, JISC (Joint Information Systems Committee) (Funder)   +2 more
core  

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source

Information security of state information systems

Безопасность информационных технологий, 2020
The purpose of the paper is to consider issues related to the security of state information systems in the Russian Federation. The relevance of these issues is primarily due to the fact that the number of cyber-attacks (causing significant damage to the ...
Rustem V. Penerdji, Grigory P. Gavdan
doaj   +1 more source

INSPIRAL: investigating portals for information resources and learning. Final project report [PDF]

, 2001
INSPIRAL's aims were to identify and analyse, from the perspective of the UK HE learner, the nontechnical, institutional and end-user issues with regard to linking VLEs and digital libraries, and to make recommendations for JISC strategic planning and ...
Brown, S., Currier, S., Ekmekioglu, F.C., JISC (Joint Information Systems Committee) (Funder)   +3 more
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Social Media Data Privacy Related to Security Awareness and Student Trust Regarding Data on Instagram

HighTech and Innovation Journal
Instagram, as one of the most popular social media sites, has brought many new trends. Many people use Instagram to express themselves or share content through photos and videos. While social media data privacy is important, many people still share their
Yohannes Kurniawan, Bella Natalia, Windy Pratama, Ni Luh Gede Aninda Kesuma Devi   +3 more
doaj   +1 more source

An Enhanced Partitioning Approach in SpatialHadoop for Handling Big Spatial Data

International Journal of Computational Intelligence Systems, 2023
SpatialHadoop could handle spatial data operations in a low partitioning execution time compared to the traditional Hadoop. However, developing an efficient and an accurate partitioning algorithm is still a research field opened to many researchers ...
Abdulaziz Shehab, Ahmed Elashry, Ahmed Aboul-Fotouh, Alaa Riad   +3 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source