Results 51 to 60 of about 31,728,436 (339)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Behavioral intentions in embracing cloud-based accounting information systems
International Journal of Academe and Industry ResearchIn facing the digital era and a more competitive environment, every organization is required to increasingly implement information systems that can facilitate various organizational needs.
Yenni Carolina +3 more
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Information Integration in Research Information Systems
Procedia Computer Science, 2014 Published by Curran, Red Hook ...
Matthias Jarke +2 more
openaire +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Exploiting Latent Semantic Subspaces to Derive Associations for Specific Pharmaceutical Semantics
Data Science and Engineering, 2020 State-of-the-art approaches in the field of neural embedding models (NEMs) enable progress in the automatic extraction and prediction of semantic relations between important entities like active substances, diseases, and genes.
Janus Wawrzinek +3 more
doaj +1 more source
International Journal of Computer Science and Information Technology, 2010 In this Information system age many organizations consider information system as their weapon to compete or gain competitive advantage or give the best services for non profit organizations. Game Information System as combining Information System and game is breakthrough to achieve organizations' performance.
openaire +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
Information Systems Evaluation: Approaches, Models and Methods [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2010 Objective: The present investigation attempts to study the approaches, models and methods used for evaluating information systems. To this end, all aspects and feature of information systems and main issues in evaluation of information systems were ...
Hussein Taghavi +2 more
doaj