Results 71 to 80 of about 2,787,697 (249)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

In-Vehicle Information Systems

Promet (Zagreb), 2012
The work considers different information systems, includingthe infonnation ~ystems with autonomous units, whichcany all their intelligence around with them, and those withcommunicating units, which infonn the motorist about the currentsituation of the ...
Gordana Štefančić, Antun Presečki, Suzana Andrić   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Sparse Array Design Based on the Combination of Improved Binary Grey Wolf Optimisation and Genetic Algorithm

IET Radar, Sonar & Navigation
Traditional adaptive beamforming techniques focus solely on optimising the excitation weights of array elements while neglecting the critical influence of element positioning on beamforming performance.
Weinian Li, Lichun Li, Hongyi Pan, Chaoyue Song, Siyao Tian   +4 more
doaj   +1 more source

In-Vehicle Information Systems

Promet (Zagreb), 2002
The paper considers different systems, including thesystems with autonomous units, which cany all their knowledgewith them, and those with communication units, which informthe driver about the current situation of the road system byradio or other means ...
Gordana Štefančić, Antun Presečki, Suzana Andrić   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Automated Skin Cancer Classification Using VGG16-Based Deep Learning Model [PDF]

E3S Web of Conferences
Melanoma is the most fatal type of skin cancer due to its high potential to metastasize and its early-stage similarity to benign skin lesions, such as common moles. This resemblance often leads to delayed diagnosis and treatment.
Cinthya Monica, Yustanti Wiyli, Nuryana I Kadek Dwi, Putra Cendra Devayana, Putra Raymond Wangsa, Dayu Dian Permatasari Kusuma, Faradilla Alda Ellsa, Kurniasari Calycha Irmalia   +7 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

RECOGNITION DESIGN OF LICENSE PLATE AND CAR TYPE USING TESSERACT OCR AND EmguCV

CommIT Journal, 2012
The goal of the research is to design and implement software that can recognize license plates and car types from images. The method used for the research is soft computing using library of EmguCV.
Antonius Herusutopo, Rizky Zuhrudin, Willy Wijaya, Yuka Musiko   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source