Results 181 to 190 of about 86,451 (215)

Assessing safety in the RTS,S/AS01 malaria vaccine implementation programme: an overview and comparison of methods. [PDF]

Malar J
Schellenberg D, Hamel M, Njuguna P, Furrer E, Praet N, Balakrishnan MR, Jain S, Maiga D, Schuerman L, Whitney CG.   +9 more
europepmc   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Genomic Survey of Carbon Monoxide Dehydrogenases Reveals Their Widespread Distribution in Marine Habitats. [PDF]

Environ Microbiol Rep
Chongdar N, Goyal A, Damare SR.
europepmc   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

What are the primary care physicians and cardiologists talking about? a cross-sectional analysis of two telemedicine services in Rio de Janeiro, Brazil. [PDF]

BMC Prim Care
Graever L, Karunananthan S, Abitbol RA, de Castro da Silva GP, Dos Santos LPR, Dias MB, Melo MM, da Fonseca VBP, Savassi LCM, Issa AFC, Frølich A, Gomes MK, Silva JRLE, Liddy C, Dominguez H.   +14 more
europepmc   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Pre-diagnostic biomarkers and risk of stress-related disorders: a cohort study based on electronic health records. [PDF]

BMC Med
Peltola AA, Khan E, Tirkkonen A, von Bonsdorff MB, Jylhävä J, Lin J.   +5 more
europepmc   +1 more source

Toxicological profiling and health hazard characterization of pesticides widely used in Tanzania unmarked. [PDF]

Toxicol Rep
Kapeleka JA, Ngowi A.
europepmc   +1 more source

Impact of an evolving classification system on diffuse glioma repositories: experience from the Sydney brain tumour bank. [PDF]

J Neurooncol
Satgunaseelan L, Xian E, Madani D, Gamage KK, Hallal SM, Gorolay V, Sim HW, Mason S, Buckland ME, Shivalingam B, Alexander KL.   +10 more
europepmc   +1 more source