Results 111 to 120 of about 6,758,826 (299)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The SIKS/BiGGrid Big Data Tutorial [PDF]
The School for Information and Knowledge Systems SIKS and the Dutch e-science grid BiG Grid organized a new two-day tutorial on Big Data at the University of Twente on 30 November and 1 December 2011, just preceding the Dutch-Belgian Database Day.
Hiemstra, Djoerd +2 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A Novel Hybrid Deep Learning Architecture for Dynamic Hand Gesture Recognition
Hand gestures are a form of natural communication used in human-computer interaction, however, when gestures are video-based, extraction of features for classification is complex.
David Richard Tom Hax +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Global Coastal Sea Surface Wind Field Correction Method for HY-2C Scatterometer
The coastal sea surface wind (SSW) field can be influenced by factors like land pollution and land terrain characteristics, resulting in lower accuracy than the open ocean.
Lanjie Zhang +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Domain adaptation for driver's gaze mapping for different drivers and new environments
Distracted driving is a leading cause of traffic accidents, and often arises from a lack of visual attention on the road. To enhance road safety, monitoring a driver's visual attention is crucial.
Ulziibayar Sonom-Ochir +3 more
doaj +1 more source

