Results 81 to 90 of about 1,546,634 (267)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

An intelligent LinkNet-34 model with EfficientNetB7 encoder for semantic segmentation of brain tumor

Scientific Reports
A brain tumor is an unnatural expansion of brain cells that can’t be stopped, making it one of the deadliest diseases of the nervous system. The brain tumor segmentation for its earlier diagnosis is a difficult task in the field of medical image analysis.
Adel Sulaiman, Vatsala Anand, Sheifali Gupta, Mana Saleh Al Reshan, Hani Alshahrani, Asadullah Shaikh, M. A. Elmagzoub   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Effective k-nearest neighbor models for data classification enhancement

Journal of Big Data
Imbalanced class distributions and class overlaps are major problems that are often associated with the classifier’s decreased performance. To lessen their impact, the literature continues to introduce methods, including kNN extensions.
Ali A. Amer, Sri Devi Ravana, Riyaz Ahamed Ariyaluran Habeeb   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Assessing green area changes in Najran City, Saudi Arabia (2013–2022) using hybrid deep learning techniques

Open Geosciences
Advances in remote sensing technology have facilitated the assessment of land vegetation and agricultural development using satellite images. This study’s normalized difference vegetation index (NDVI) is vital in assessing vegetation coverage and ...
Ali Elham, Alshari Eman A., Shamsan Ahlam, Alqhatani Abdulmajeed, Al-Wagih Khalil, Olayah Fekry, Senan Ebrahim Mohammed, Aljubayri Mohammed   +7 more
doaj   +1 more source

ResViT HybridNet: a fusion of ResNet50 and Vision Transformer for banana leaf disease identification

Automatika
Banana leaf diseases such as Cordana, Sigatoka, and Pestalotiopsis significantly reduce crop yield and quality, necessitating accurate and early detection for effective management.
Vishnu Kant, Sheifali Gupta, Samar M. Alqhtani, M. A. Elmagzoub, Mana Saleh Al Reshan, Mousa Alalhareth, Asadullah Shaikh   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source