Results 141 to 150 of about 3,709,120 (314)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Integrated information technology strategic plan [PDF]
, 2005 reportThe Integrated Information Technology Strategic Plan is the result of ongoing agreement and consensus of representative faculty, students, and professional information technology staff to serve client needs within the scope and mission of the ...
Information Technology Council
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Information Technology and Sustainability in the Information Society
International Journal of Communication, 2017 The sustainability concept has developed in a policy context. Its main relevance has been in policy forums such as the United Nations Conference on Environment and Development and the United Nations Conference on Sustainable Development. In the realm of
Christian Fuchs
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
State of Connecticut Department of Information Technology; Connecticut Department of Information Technology; DOIT [PDF]
, 2007 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Jan. 5, 2011).; At head of title: State of Connecticut.; Harvested from the web on 1/5/11Official website of the Connecticut Department of Information Technology ...
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Production Technology, Information Technology, and Vertical Integration Under Asymmetric Information. Part I [PDF]
Problems and Perspectives in Management, 2004 Gamal Atallah
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Information Technology and Information Approach in Historical Research
RUDN Journal of Russian History, 2011 The article is devoted to the evolution of theoretical and applied aspects of information technology in historical research. The author shows that the development of theoretical concepts of an information approach, methodological and technological ...
I M Garskova
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source