Results 51 to 60 of about 76,429 (255)
RAUSP: Revista de Administração da Universidade de São PauloThis study proposes an analysis of non-operational mechanisms that can impact the effectiveness of information technology governance in the Brazilian public administration.
Leonel Cerqueira Santos +1 more
doaj +1 more source
JuTISI (Jurnal Teknik Informatika dan Sistem Informasi), 2015 — Information technology has become an important part in the organization, particularly for profit-oriented business organizations. PT Nikkatsu Electric Work is one of the companies that require information technology governance. Information technology
Rauf Fauzan, Rani Latifah
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Effective Information Technology Governance Mechanisms: An Australian Study
Gadjah Mada International Journal of Business, 2006 Growing importance of information technology (IT), as a strategic factor for organizations in achieving their objectives, have raised the concern of organizations in establishing and implementing effective IT governance.
Syaiful Ali
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Information Technology Adoption, Corporate Governance and Bank Performance
Journal of Information Systems Engineering and Business Intelligence, 2018 Many academicians and practitioners have been acknowledging that information technology (IT) adoption could improve company performance. However, previous research indicates contradictory evidence.
Umi Muawanah, Gunadi Gunadi
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Information technology governance framework for improving organisational performance
South African Journal of Information Management, 2019 Background: Following the corporate failures of the 1990s, factors identified as evidence for these failures extended beyond just weak or ineffective corporate governance models, codes and legislation.
Anyetei Ako-Nai, Anesh M. Singh
doaj +1 more source