Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
The Fundamental Tension in Integrated Information Theory 4.0's Realist Idealism. [PDF]
Cea I, Negro N, Signorelli CM.
europepmc +1 more source
Bohr: Physique atomique et connaissance humaine/Becker: Theorie der Elektrizität Bd. I/Schaefer und Päsler: Einführung in die Theoret. Physik Bd. I/MacDonald: Thermoelectricity: An Introduction to the Principles/Brillouin: Science and Information Theory/Bradley: Shock Waves in Chemistry and Physics/Pirani und Yarwood: Principles of Vacuum Engineering/Chase: Nuclear Pulse Spectrometry [PDF]
Klaus Pöschl+7 more
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ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
A Theory of Inaccessible Information
What would be the consequences if there were fundamental limits to our ability to experimentally explore the world? In this work we seriously consider this question. We assume the existence of statements whose truth value is not experimentally accessible.
openaire +3 more sources
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Japanese society sponsors meeting on microwaves and information theory [PDF]
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Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Causal Inference for Heterogeneous Data and Information Theory. [PDF]
Hlaváčková-Schindler K.
europepmc +1 more source