Results 141 to 150 of about 21,261,657 (350)

The impact of food safety regulatory information intervention on enterprises’ production violations in China: a randomized intervention experiment

open access: yesFrontiers in Sustainable Food Systems
The prevalence of unsafe food poses a widespread challenge across numerous nations. Despite the continuous investments by the Chinese government in food safety regulation, the condition of food safety in China is still not ideal and requires substantial ...
Tong Zhao, Taiping Li, Dan Liu, Yun Luo
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Open Source Tools to Support Teaching Agile Software Development [PDF]

open access: yes, 2014
Learning agile software development methodologies are important due to the popularity of agility in software industry. Agile software development has several practices and each practice needs specific tools to work with.
Adhy, Satriyo, Wisnu Wirawan, Panji
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Trends in Smart City Development [PDF]

open access: yes, 2017
This report examines the meanings and practices associated with the term 'smart cities.' Smart city initiatives involve three components: information and communication technologies (ICTs) that generate and aggregate data; analytical tools which convert ...
Elias Stahl, Nicole Dupuis
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Financial First Aid Tool Kit: Financial Tips for Accumulating and Managing Wealth [PDF]

open access: yes, 2013
Wealth building is an anti-poverty strategy that helps low- and moderate-income people move toward greater self-sufficiency by accumulating assets, the basis of wealth.

core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Wuppertal Institute designguide: background information & tools [PDF]

open access: yes, 2013
Our perception of design is changing, for design today is no longer concerned only with aesthetics. Now the key factors are interdisciplinary competence and approaches to problem solving. Both politicians as well as businesses recognise design's hybridity and increasingly implement it as a driver of sustainable development (see Chap. 2: Design as a Key
Liedtke, Christa   +5 more
openaire   +1 more source

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