Results 101 to 110 of about 4,790,209 (297)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Improving community structure strategy for efficiently enhancing Internet transmission performance

open access: yesTongxin xuebao, 2013
An efficient weakening community structure strategy (WCS) by adding links to the existing networks was propose,which could enhance Internet transmission performance.Internet topology reconstruction could be realized by WCS strategy,because lightpaths ...
Jun CAI, Shun-zheng YU
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Analysis of lifestyle and physical culture and sports of students

open access: yesСтатистика и экономика, 2016
ARTICLE RETRACTEDThe article reviewed the importance and necessity of sport and physical education at the present stage. The article describes the trend of health deterioration of young people as the consequence of a wrong lifestyle, alcohol, tobacco ...
Ol’ga P. Kokoulina
doaj   +1 more source

Constrained Codes for Joint Energy and Information Transfer

open access: yes, 2013
In various wireless systems, such as sensor RFID networks and body area networks with implantable devices, the transmitted signals are simultaneously used both for information transmission and for energy transfer.
Erkip, Elza   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Novos enfoques no campo da Ciência da Informação: uma discussão sobre a aplicabilidade do conceito de regime de informação em arranjos produtivos locais

open access: yesPerspectivas em Ciência da Informação
Discute-se a aplicabilidade do conceito de regime de informação focalizado em arranjos produtivos locais como uma forma de contribuição para a discussão de práticas e ações informacionais.
Adriane Maria Arantes de Carvalho
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Recent Advances in Joint Wireless Energy and Information Transfer

open access: yes, 2014
In this paper, we provide an overview of the recent advances in microwave-enabled wireless energy transfer (WET) technologies and their applications in wireless communications. Specifically, we divide our discussions into three parts. First, we introduce
Bi, Suzhi, Ho, Chin Keong, Zhang, Rui
core   +1 more source

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