Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Refrigerant forced-convection condensation inside horizontal tubes [PDF]
High vapor velocity condensation inside a tube was studied theoretically. The heat transfer coefficients were calculated by the momentum and heat transfer analogy.
Bae, S. +8 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Oregon T2 Center's Oregon roads newsletter summer 1998-
Information about serial cessation provided by Oregon Department of Transportation on May 25, 2022."A quarterly publication for local governments responsible for roads, bridges, and public transportation."Title from captionMode of access: Internet from ...
core
School students, information retrieval and transfer [PDF]
This study sought to examine the views of students, teachers and teacher librarians on students\u27 attitudes to, use of, and reflections on, information retrieval, when completing curricular assignments.
Herring, James Edward
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Knowledge Transfer Processes in the IS Offshore Outsourcing Transition: A Conceptual Model
Despite promising cost saving potential, many offshore software projects fail to realize the expected benefits. A frequent source of failure lies in the insufficient transfer of knowledge during the transition phase.
Dibbern, Jens, Krancher, Oliver Jürgen
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Analysis of lifestyle and physical culture and sports of students
ARTICLE RETRACTEDThe article reviewed the importance and necessity of sport and physical education at the present stage. The article describes the trend of health deterioration of young people as the consequence of a wrong lifestyle, alcohol, tobacco ...
Ol’ga P. Kokoulina
doaj +1 more source

