Results 231 to 240 of about 18,689,391 (306)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Multi-Sensor Learning Enables Information Transfer Across Different Sensory Data and Augments Multi-Modality Imaging. [PDF]

IEEE Trans Pattern Anal Mach Intell
Zhu L, Chen Y, Liu L, Xing L, Yu L.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Emergence of input selective recurrent dynamics via information transfer maximization. [PDF]

Sci Rep
Kanemura I, Kitano K.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A new directionality index based on high-resolution joint symbolic dynamics to assess information transfer in multivariate networks. [PDF]

Front Neurosci
Schulz S, Schumann A, Bär KJ, Haueisen J, Seifert G, Voss A.   +5 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Identifying practices of information transfer between the hospital and primary care for older adults: a scoping review protocol. [PDF]

BMJ Open
Yang D, Alkot M, Quaiattini A, Lessard S, Zaripova A, Pavoni C, Couture S, Desmarais P, Huang YQ, McDonald EG, Richer C, Chabot J, Pageau F, Tannou T, Layani G, Rouabhia D, Calafiore M, Fink K, Yilmaz G, Jean-Baptiste B, Godard-Sebillotte C.   +20 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

The tuning of tuning: How adaptation influences single cell information transfer. [PDF]

PLoS Comput Biol
Zeldenrust F, Calcini N, Yan X, Bijlsma A, Celikel T.   +4 more
europepmc   +1 more source