Results 51 to 60 of about 958,334 (298)

Simultaneous RIS Adjustment and Transmission Based on Markov Chain Monte Carlo and Simulated Annealing

open access: yesIEEE Open Journal of the Communications Society
Reconfigurable Intelligent Surface (RIS) is a promising solution for enhancing the coverage and capacity of current and future wireless systems. To fully exploit its potential, RIS requires a fast adjustment algorithm, which determines the optimal ...
Ilya Burtakov   +3 more
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The rapidly growing landscape of RAS inhibitors: from selective allele blockade to broad inhibition strategies

open access: yesMolecular Oncology, EarlyView.
RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Enabling the Internet of Things With Wi-Fi Halow—Performance Evaluation of the Restricted Access Window

open access: yesIEEE Access, 2019
IEEE 802.11ah, a new amendment to the Wi-Fi standard, adapts Wi-Fi networks to the emerging Internet of Things (IoT). A key component of .11ah is the Restricted Access Window (RAW), a new channel access mechanism, which reduces contention when even ...
Evgeny Khorov   +6 more
doaj   +1 more source

Intelligent hybrid automatic repeat request retransmission for multi‐band Wi‐Fi networks

open access: yesIET Communications, 2021
With the increase of Wi‐Fi connections and throughput, the problems posed by unreliable connection and unstable delay need to be urgently solved through advanced methods.
Zhou Wang   +4 more
doaj   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

open access: yesFEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

New Approaches to the Integration of Navigation Systems for Autonomous Unmanned Vehicles (UAV)

open access: yesSensors, 2018
The article presents an overview of the theoretical and experimental work related to unmanned aerial vehicles (UAVs) motion parameters estimation based on the integration of video measurements obtained by the on-board optoelectronic camera and data from ...
Ivan Konovalenko   +6 more
doaj   +1 more source

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