Results 51 to 60 of about 990,651 (297)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Preserving Information in Neural Transmission [PDF]

The Journal of Neuroscience, 2009
Along most neural pathways, the spike trains transmitted from one neuron to the next are altered. In the process, neurons can either achieve a more efficient stimulus representation, or extract some biologically important stimulus parameter, or succeed at both.
Lawrence C, Sincich, Jonathan C, Horton, Tatyana O, Sharpee   +2 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Power Allocation for Downlink NOMA Heterogeneous Networks

IEEE Access, 2018
Non-orthogonal multiple access (NOMA) and heterogeneous network (HetNet) are two significant and promising enabling techniques to further improve overall system performance for nextgeneration mobile communication systems.
Dadong Ni, Li Hao, Quang Thanh Tran, Xiaomin Qian   +3 more
doaj   +1 more source

Demographic indicators, models, and testing

Discrete and Continuous Models and Applied Computational Science, 2023
The use of simple demographic indicators to describe mortality dynamics can obscure important features of the survival curve, particularly during periods of rapid change, such as those caused by internal or external factors, and especially at the oldest ...
Gregory A. Shilovsky, Alexandr V. Seliverstov, Oleg A. Zverkov   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Origin and diversity of Capsella bursa-pastoris from the genomic point of view

BMC Biology
Background Capsella bursa-pastoris, a cosmopolitan weed of hybrid origin, is an emerging model object for the study of early consequences of polyploidy, being a fast growing annual and a close relative of Arabidopsis thaliana.
Aleksey A. Penin, Artem S. Kasianov, Anna V. Klepikova, Denis O. Omelchenko, Maksim S. Makarenko, Maria D. Logacheva   +5 more
doaj   +1 more source

Transcriptional Regulation of Carbohydrate Utilization Pathways in the Bifidobacterium Genus

Frontiers in Microbiology, 2016
Bifidobacteria, which represent common commensals of mammalian gut, are believed to have positive effects on human health. The influence of certain non-digestible carbohydrates (and their use as so-called prebiotics) on growth and metabolic activity of ...
Matvei S Khoroshkin, Semen A Leyn, Douwe eVan Sinderen, Dmitry A Rodionov, Dmitry A Rodionov   +4 more
doaj   +1 more source

Adaptive Rescaling Maximizes Information Transmission [PDF]

Neuron, 2000
Adaptation is a widespread phenomenon in nervous systems, providing flexibility to function under varying external conditions. Here, we relate an adaptive property of a sensory system directly to its function as a carrier of information about input signals. We show that the input/output relation of a sensory system in a dynamic environment changes with
Brenner, Naama, Bialek, William, de Ruyter van Steveninck, Rob   +2 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source