Results 81 to 90 of about 438,636 (298)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Innovation and Information Acquisition Under Time Inconsistency and Uncertainty [PDF]

We propose to analyse the hyperbolic discounting preferences effect on the innovator's research investment decision. Investing in research allows him to acquire information, and then to reduce the uncertainty of the risks of his project.
Caroline Orset, Sophie Chemarin
core  

Measuring Forecast Uncertainty by Disagreement: The Missing Link [PDF]

Using a standard decomposition of forecasts errors into common and idiosyncratic shocks, we show that aggregate forecast uncertainty can be expressed as the disagreement among the forecasters plus the perceived variability of future aggregate shocks ...
Kajal Lahiri, Xuguang Sheng
core   +3 more sources

An Earth System Model Ensemble Forced With Probabilistic Emissions: Demonstration and Prospects for Climate Risk Assessment

Earth's Future
Future projections of climate change are uncertain, in part because of uncertainty in future greenhouse gas emissions. However, current widely used emission scenarios and related physical climate projections have no probabilities associated with them ...
Jeremy Fyke, Neil C. Swart, David Huard
doaj   +1 more source

Modelling for uncertainty in HBIM processes

Vitruvio: International Journal of Architectural Technology and Sustainability
The application of HBIM for the information management of historical buildings is often hindered by the presence of uncertainty due to limited geometric information and documentation at the time of modelling; controlling and organising this level of ...
Alessia Mazzei, Letizia Martinelli, Tommaso Empler, Luciano Cessari, Elena Gigliarelli   +4 more
doaj   +1 more source

Using the Wild Bootstrap to Quantify Uncertainty in Mean Apparent Propagator MRI

Frontiers in Neuroinformatics, 2019
Purpose: Estimation of uncertainty of MAP-MRI metrics is an important topic, for several reasons. Bootstrap derived uncertainty, such as the standard deviation, provides valuable information, and can be incorporated in MAP-MRI studies to provide more ...
Xuan Gu, Xuan Gu, Anders Eklund, Anders Eklund, Anders Eklund, Evren Özarslan, Evren Özarslan, Hans Knutsson, Hans Knutsson   +8 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Assessment of risks in construction [PDF]

Строительство уникальных зданий и сооружений, 2013
The realization of any investment project involves various types of risks, due to the presence of uncertainty in the economic activity of the enterprise. The reasons of occurrence risks are not the full amount of information about the future Distinction
Tatiana Fedorovna Morozova, Kinayat Laula Argenovna, Kinayat Ayan Zhaksibekuli   +2 more
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Decision-making under epistemic, strategic and institutional uncertainty during COVID-19: findings from a six-country empirical study

BMJ Global Health
Background Uncertainty is defined as limited knowledge or lack of predictability about past, present or future events. The COVID-19 pandemic management was significantly impacted by uncertainty, as the gaps between existing information and the necessary ...
Clare Wenham, Alexandra L Phelan, Winifred Ukponu, Sumegha Asthana, Tahmina Shirin, Claire J Standley, Adachioma Chinonso Ihueze, Sanjana Mukherjee, Ibrahim B Gobir, Mohannad Al Nsour, JJ Woo, Mohammad Mushtuq Husain, Nevashan Govender, Roujia Lin, Sumit Asthana, Renee Vongai Mutare   +15 more
doaj   +1 more source