Results 131 to 140 of about 18,075,925 (282)

Characterising performance information use in the primary healthcare systems of El Salvador, Lebanon and Malawi: multiple qualitative case study protocol. [PDF]

BMJ Open, 2022
Munar W, Wahid SS, Makwero M, El-Jardali F, Dullie L, Yang WC.   +5 more
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Evaluation of the Coordinated Development of the “Population–Economy” in Counties Within the Beijing–Tianjin–Hebei Urban Agglomeration

Land
The coordinated development of urban agglomerations is a crucial means of establishing a territorial development and protection pattern with complementary advantages and high-quality development.
Yanmin Ren, Yanyu Zhang, Shuhua Li, Yu Liu, Lan Yao, Linnan Tang   +5 more
doaj   +1 more source

Conceptual preferences can be transmitted via selective social information use between competing wild bird species. [PDF]

R Soc Open Sci, 2022
Forsman JT, Kivelä SM, Tolvanen J, Loukola OJ.   +3 more
europepmc   +1 more source

Revisiting the Use of Customer Information for CRM [PDF]

For the past decade, customer relationship management (CRM) has been one of the priorities in marketing research and practice. However, many of the CRM systems did not perform as the companies expected.
Becker, Jan U., Reimer, Kerstin
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Health information use and associated factors among healthcare professionals in Ilu Aba Bor zone, Oromia region, Ethiopia: an institution-based cross-sectional study. [PDF]

BMJ Open, 2023
Negera D, Zewdie A, Kera AM, Degefa GH.
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Introducing the UK Crop Microbiome Cryobank data resource, AgMicrobiomeBase, with case studies and methods on metabarcoding analyses

Environmental Microbiome
Background Here, we describe AgMicrobiomeBase as an output of the UK Crop Microbiome Cryobank (UKCMCB) project, including details of the underlying meta-barcode sequence-based methods and three microbiome analysis case studies.
Payton To Yau, Rodrigo G. Taketani, J. Miguel Bonnin, Helen Stewart, Catriona M.A. Thompson, Ian M. Clark, Tim H. Mauchline, Jacob G. Malone, Matthew J. Ryan, Susan Jones, Nicola Holden   +10 more
doaj   +1 more source