Results 61 to 70 of about 5,466,361 (243)

Transformations of Copyright and Neighboring Rights in the Digital Era

open access: yesВестник Кемеровского государственного университета. Серия: гуманитарные и общественные науки
The rapid technological development has introduced artificial intelligence (AI) to creative industries. As a result, institutions of copyright and neighboring, or related, rights are facing new challenges that require new legal approaches.
Vladislav A. Syrbo, Daria A. Krapivina
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Barriers and Facilitators to Research Use Among Allied Health Practitioners: A Mixed-Method Approach to Assessment

open access: yesEvidence Based Library and Information Practice, 2011
Objectives – The disparity between what is known to be effective and what is done in practice points to barriers to research use among health practitioners.
Mary Dunne
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

An Examination of Factors Influencing National Reputation of India Among South Asians on Social Media

open access: yesInternational Journal of Communication, 2021
Social media play a central role in governments’ communication with foreign citizens, but little is done to understand how such platforms build national reputation. To fill this research gap, the study examines online engagement, online social relations,
Nisha Garud-Patkar
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

THE USE OF GEOGRAPHIC INFORMATION SYSTEMS IN SELECTING THE MOST SUITABLE SITES FOR TOURISM PROJECTS IN EL DRIOUCH (NORTHEASTERN MOROCCO) [PDF]

open access: yesGeo Journal of Tourism and Geosites
This study explores the potential of using Geographic Information Systems (GIS) in spatial analysis to identify the most suitable locations for establishing tourism projects in the Driouch Province.
Elkallouchi MOHAMED, Bouguelba SMAIL
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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