, 1976 Title devised by cataloguer from inscription.; Part of the Australian Information Service collection.; Inscriptions: Typewritten information about the find on verso; "Mr Charles Dortch at work in the rubbish tip where he found the Aboriginal artifacts ...
Brown, Mike, photographer.
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Information gaps across care interfaces in home care and patient safety incidents: a cross-sectional survey of home care professionals in Finland. [PDF]
BMJ OpenSylgren I, Jämsen E, Torkki P.
europepmc +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
State and Local Policymakers' Engagement with Neuroscience to Improve Health Policy in the United States. [PDF]
eNeuroLevine AS, Mathews DJH, Boyd JL.
europepmc +1 more source
Learning to work between information infrastructures [Elektronisk resurs]
, 2019 This study investigates the implications of the interplay of multiple information infrastructures to learning and conducting work and to its related information work practices, and how the materialities of work and its infrastructures play into their ...
Huvila, Isto,
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Efficacy of a training program to support the application of the Guideline Evidence-based Health Information: a randomized controlled trial and process evaluation. [PDF]
TrialsLühnen J +5 more
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source