Results 31 to 40 of about 59,468 (296)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

THE USE OF INFORMATION TECHNOLOGIES IS IN TEACHING OF ECONOMIC DISCIPLINES

open access: yesÌнформаційні технології в освіті, 2010
The essence of informational technology, informational resources and distance technologies are analyzed. The use of the following forms are determined as he high mobile level, engaged a large number of students, and belonged to the one of the most ...
O. Nosova, O. Makovoz
doaj  

Supportive Care Needs of Patients with Breast Cancer Who Self-Identify as Black: An Integrative Review

open access: yesCurrent Oncology
Black-identifying patients face many barriers to the receipt of equitable breast cancer care; however, little is currently known about the unique needs of this patient population, particularly in Canada.
Etienne Oshinowo   +14 more
doaj   +1 more source

Étudier les biens communs par les changements institutionnels : régimes de propriété autour des races animales face à l’innovation génomique

open access: yesRevue de la Régulation, 2014
This article aims at using the analytical framework proposed by Schlager and Ostrom (1992) for a dynamic description of property rights in the management of common resources, here animal genetic resources.
Julie Labatut   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Oregon Water Resources Department rulemaking

open access: yes, 2022
Title from PDF caption (viewed on November 22, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

INVESTMENTS IN RETAIL TRADE AND ITS ROLE IN REGIONAL ECONOMIC DEVELOPMENT: CASE OF REPUBLIC OF CRIMEA [PDF]

open access: yesKrymskij Naučnyj Vestnik, 2015
In this articles evaluated directions of investments to retail in Republic of Crimea, which will provide access for industry of the region to the modern level of development.
Oksana Karashсhuk
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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