Results 61 to 70 of about 379,527 (298)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Informational Aesthetics—What Is the Relationship between Art Intelligence and Information?

open access: yesProceedings, 2020
The author examines the notion of informational aesthetics. The origin of aesthetics lies in Epicurus’s notion of aesthesis and the integration of artistic activity within ethics and the ‘good life’—as in the aesthetic theory and practice of the East ...
John Holgate
doaj   +1 more source

IMPLEMETING THE E-MANAGEMENT WITHIN THE SMALL AND MEDIUM ENTERPRISES IN ROMANIA - A PREMISE FOR ENSURING A DURABLE DEVELOPMENT [PDF]

open access: yes
The present article introduces the ways and advantages of implementing the e-Management systems, based on decision assistance software, within the Romanian small and medium enterprises that have set as main goal for the near future the durable ...
Corneliu Gârjoabă, Dan Ilie Morega
core  

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

“SOFT POWER”, COMMUNICATION AND THE PROBLEM OF HUMANITARIAN CRISIS [PDF]

open access: yes, 2016
The article is devoted to the philosophical inquiry of the worldview connection between soft power, information and humanitarian crisis of modernity. The purpose of the work is the integrative philosophical analysis of the expression of the “soft power ...
Chernyshov, V. A.
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

The Mass-Media in Modern Russia

open access: yesRUDN Journal of Political Science, 2008
The article is devoted to the analysis of current condition of informational-communicative system of Russia, which, as author noted, truly reflects social and political processes in the society in every period of its development.
V A Annikova
doaj  

Hungary and the Information Society: getting a grip on territorial impacts [PDF]

open access: yes
Since the political, social and economic transition was launched in the late eighties, regional differences, measurable on various spatial scales, have considerably increased within Hungary.
Sarolta Németh
core  

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