Results 121 to 130 of about 4,891,122 (284)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

INFORMED CONSENT – RIGHT OR BURDEN

open access: yesZdravniški Vestnik, 2016
Informed consent is legal institute that was introduced in the research area to prevent possible abuses in human research. Almost a century later it was introduced also in general medicine outside the research area.
Borut Stražišar, Branka Stražišar
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hubungan Antara Tingkat Kepuasan Pasien Terhadap Pemberian Informed Consent Sebelum Tindakan Operasi Di RSUD Dr.Moewardi [PDF]

open access: yes, 2014
Praktik pelayanan medis di Indonesia menerima pernyataan mengenai informed consent, yang tercantum dalam Permenkes No. 585 Tahun 1989 tentang persetujuan tindakan medik, informed consent didefinisikan sebagai persetujuan yang diberikan oleh pasien atau ...
, Bd. Sulastri, S.Kp., M.Kes   +2 more
core  

Earning Legitimacy: Participation, Intellectual Property and Informed Consent [PDF]

open access: yes
A booklet linking politics and practice aimed at museum practitioners and researchers working with ...
Graham, HC, Mason, R, Nayling, N
core  

Patient-reported conformity of informed consent procedures and participation in clinical research [PDF]

open access: yes, 2017
Background: There is growing evidence that the quality of informed consent in clinical research is often sub-optimal. Aims: To explore the conformity of patient recruitment with recommended informed consent procedures among patients who were invited to ...
Agoritsas, T., Perneger, T.V.
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Informed consent for telemedicine

open access: yesJournal of Family Medicine and Primary Care, 2020
Himel Mondal   +2 more
doaj   +1 more source

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