CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani+11 more
wiley +1 more source
Is informed consent in neonatal randomised controlled trials ritual?
Malcolm Levene+2 more
openalex +1 more source
Informed Consent in the Medical Care of Transgender and Gender-Nonconforming Patients.
Timothy Cavanaugh+2 more
semanticscholar +1 more source
ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu+15 more
wiley +1 more source
Enhancing Informed Consent Forms for Medical Devices: International Regulatory Guidance and Ethical Recommendations. [PDF]
Peycheva OM+3 more
europepmc +1 more source
Analysis of Soluble Interleukin‐2 Receptor as a Prognostic Biomarker in NMOSD and MOGAD
ABSTRACT Objective Soluble interleukin‐2 receptor (sIL‐2R) is a biomarker for T cell activity. T cells are involved in neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) pathogenesis. However, sIL‐2R has so far not been evaluated in these conditions.
Philipp Klyscz+8 more
wiley +1 more source
Protocol: Strategies to Enhance Inclusion in Informed Consent Practice for People With Vision and/or Hearing Support Needs: A Systematic Review. [PDF]
O'Hare F+8 more
europepmc +1 more source
Allegations of Failure to Obtain Informed Consent in Spinal Surgery Medical Malpractice Claims
Jennifer N Grauberger+6 more
semanticscholar +1 more source
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García+3 more
wiley +1 more source