Results 81 to 90 of about 4,891,122 (284)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Permasalahan Informed Consent Penelitian Kesehatan

open access: yesJurnal Vektor Penyakit, 2017
Informed consent is consent given by research subjects after he obtained the information completely. One ofthe most important problems is the lack ofunderstanding of the subject of the content of the informed consent  form  caused by the use of ...
Made Agus Nurjana
doaj   +1 more source

Informed Consent and the Research Process: Following Rules or Striking Balances? [PDF]

open access: yes
Gaining informed consent from people being researched is central to ethical research practice. There are, however, several factors that make the issue of informed consent problematic, especially in research involving members of groups that are commonly ...
Graham Crow   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Informed consent in clinical research

open access: yesCHRISMED Journal of Health and Research, 2015
Worldwide, the goal of clinical research is to develop knowledge that improves human health or augments understanding of human biology. In biomedical research, two pillars have been identified - informed consent and independent review by an Ethics ...
Saurabh R Shrivastava   +2 more
doaj   +1 more source

ANALISIS PERSETUJUAN TINDAKAN KEDOKTERAN (INFORMED CONSENT)DALAM RANGKA PERSIAPAN AKREDITASI RUMAH SAKIT DI INSTALASI BEDAH SENTRAL RSUD KOTA SEMARANG [PDF]

open access: yes, 2015
Pelaksanaan informed consent salah satu aspek penting dalam elemen penilaian akreditasi rumah sakit. Permenkes RI no. 290 tahun 2008 mengatur perlunya informed consent pada pasien atas tindakan medis yang akan diterimanya.
FIKRIYA, KHASNA
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Informed Consent in Adult Psychiatry

open access: yesOman Medical Journal, 2013
This article addresses some of the groundwork of informed consent in people with mental illness whose decision-making capacity has obviously been compromised.
Ahmed Bait Amer
doaj   +1 more source

Analisis Kelengkapan Informed Consent Pasien PRA Operasi Katarak di RS. Khusus Mata Smec Medan Tahun 2018 [PDF]

open access: yes, 2018
Rekam medis merupakan berkas yang berisikan catatan dan dokumen tentang identitas, pemeriksaan, pengobatan, tindakan, dan pelayanan lain yang telah diberikan kepada pasien.
Simanjuntak, E. (Esraida)   +1 more
core  

Home - About - Disclaimer - Privacy