Results 101 to 110 of about 1,017,822 (240)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Effective information spreading based on local information in correlated networks [PDF]

open access: yesarXiv, 2016
Using network-based information to facilitate information spreading is an essential task for spreading dynamics in complex networks, which will benefit the promotion of technical innovations, healthy behaviors, new products, etc. Focusing on degree correlated networks, we propose a preferential contact strategy based on the local network structure and ...
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

La inteligencia emocional y su influencia en la gestión personal y productiva de los microempresarios

open access: yesCiencia UNEMI, 2016
On several occasions limitations observed in the management of certain entrepreneurs, canton Milagro, Guayas Province, Ecuador, who are far better than others obtained, this generated a process of investigation whose objective was to offer entrepreneurs
Velásquez-Castro, Virginia   +3 more
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

El profesorado universitario y las tecnologías de la información y de la comunicación (TIC): disponibilidad y formación

open access: yesEducatio Siglo XXI, 2011
La irrupción de las Tecnologías en la Educación Superior (TIC) ha tenido una trayectoria lenta y controvertida. En este artículo se revisan los principales hitos en su desarrollo e implantación en las Universidades Españolas recogiendo las aportaciones ...
Isabel Cantón Mayo   +1 more
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Agentividad y responsabilidad en informes de derechos humanos: el caso del estallido social chileno de 2019

open access: yesDiscurso & Sociedad
Este análisis se centra en la construcción discursiva de la responsabilidad de los agentes estatales en contextos de violaciones de derechos humanos. Nos enfocamos en un género discursivo específico, a saber, los informes de derechos humanos.
Stéphanie Pécher
doaj   +1 more source

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