Results 111 to 120 of about 1,447,604 (353)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Informes Contables de Responsabilidad Social Empresaria. [PDF]

open access: yes
El siguiente trabajo se refiere a las características de los informes contables microsociales externos e internos y sus beneficios. Su función es de suma importancia ya que permite mostrar a los distintos interesados, la gestión social del ente y a ...
Carrizo, Gabriela Cristina
core  

Responsabilidade profissional aplicada à farmacovigilância: um estudo de caso no México [PDF]

open access: yes, 2016
The international pharmacovigilance system collects adverse drug events reported by physicians in their clinical practice. Adverse drug reactions (ADR) reported are scarce. We designed a questionnaire based on a 5-point Likert scale.
Asbún-Bojalil, Juan   +2 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Los informes contables anuales y su papel en la institución del "yo" organizacional [PDF]

open access: yes, 2014
La ponencia se inscribe en la línea argumental de los estudios interdisciplinarios sobre los reportes corporativos, con énfasis en el corporate self, por lo que se ahonda en el interrogante: ¿Cómo son usados los informes contables anuales para instituir ...
Cuevas Mejía, John Jairo
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Especulación en el Cementerio viejo de Cehegín

open access: yesAlquipir, 2014
Los documentos históricos son elementos de gran valor que nos aportan gran cantidad de información. Si esta se procesa de manera adecuada puede desvelarnos elementos claves para la Historia tanto nacional como local.
Gortín
doaj  

Tendencias tecnológicas en educación [PDF]

open access: yes, 2016
Esta infografía recopila los informes de tres Instituciones que han analizado las tendencias, en diferentes ámbitos, que marcarán el futuro de la educación en el ...
Gómez Galvis, Santiago   +2 more
core  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

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