Results 141 to 150 of about 1,447,604 (353)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Not All Similarities Are Created Equal: Leveraging Data-Driven Biases to Inform GenAI Copyright Disputes [PDF]

open access: green
Uri Hacohen   +6 more
openalex   +1 more source

Development of a Measure to Inform Return-to-Duty Decision Making After Mild Traumatic Brain Injury [PDF]

open access: bronze, 2013
Mary Vining Radomski   +8 more
openalex   +1 more source

Opiniones de las comunidades autónomas sobre la cesión del IVA y de los impuestos especiales 1996-2001 [PDF]

open access: yes, 2003
La cesión parcial a las Comunidades Autónomas de régimen general del Impuesto sobre el Valor Añadido (IVA) y de los Impuestos Especiales son dos de las medidas de mayor trascendencia adoptadas con motivo de la reforma del sistema de financiación ...
Lasarte López, Rocío
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Informes rendidos al Sr. Rector de la Universidad de Antioquia

open access: yesEstudios de Derecho, 1915
Informes rendidos al Sr.
Fernando Vélez, Juan E. Martínez
doaj  

Informes Contables de Responsabilidad Social Empresaria. [PDF]

open access: yes, 2010
El siguiente trabajo se refiere a las características de los informes contables microsociales externos e internos y sus beneficios. Su función es de suma importancia ya que permite mostrar a los distintos interesados, la gestión social del ente y a ...
Carrizo, Gabriela Cristina
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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