Results 31 to 40 of about 820 (211)
Entre 1.987 y 1.991 la UNESCO publicó tres informes acerca de las bibliotecas nacionales elaborados por Sylvestre, Line y Cornish. No hay unidad de criterios a la hora de analizar el concepto de biblioteca nacional, esencialmente debido a la diversidad ...
Juan José Fuentes Romero
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
En Argentina, la demanda interna de azúcar fue provista por la industria azucarera con base en la caña, desarrollada principalmente en la región norte el país.
Daniel Moyano, Susana Bandieri
doaj +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
La Aporofobia en el contexto de la sociedad peruana: una revisión
La investigación comienza teorizando sobre aporofobia, concepto aprobado por la Real Academia Española para referirse a la fobia a los pobres. Se revisaron documentos e informes de organismos nacionales e internacionales para caracterizar, analizar y ...
Rosmery Sabina Pozo Enciso +1 more
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Public Policy Guidelines Addressing School Harassment
La presente investigación, tuvo como objetivo, dar cuenta sobre las políticas públicas que atienden el fenómeno del Acoso Escolar. Legislación internacional y nacional que orienta las intervenciones para prevenir y atender el acoso escolar.
Margarita María Cano Echeverry +1 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
TEORÍAS DE DESARROLLO ECONÓMICO Y SOCIAL: ARTICULACIÓN CON EL PLANTEAMIENTO DE DESARROLLO HUMANO
El propósito fundamental de este trabajo es discutir las principales teorías del desarrollo económico y social, y articular las mismas a los conceptos fundamentales de desarrollo humano.
Giovanni Reyes
doaj

