Results 91 to 100 of about 1,831,889 (306)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A New Approach to Bridge Infrastructure Management

open access: yes, 2013
The maintenance of bridges as a key element in transportation infrastructure has become a major concern due to increasing traffic volumes, deterioration of existing bridges and well-publicised bridge failures.
Ho, Tinkin   +5 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Application of 3D finite-element analysis to predict ground displacement from horizontal directional drilling in highly compressible organic clays [PDF]

open access: yesE3S Web of Conferences
Horizontal Directional Drilling (HDD) is a proven trenchless methodology for utilities installation below critical infrastructure that limits predicted ground displacement to 5mm.
Ramadan Mohamad   +2 more
doaj   +1 more source

Data for: Characteristics of Selected Open Infrastructures, 2024 State of Open Infrastructure Report

open access: yes
<p>The State of Open Infrastructure report provides an annual snapshot of general characteristics for open infrastructures (OIs) listed in Invest in Open Infrastructure’s (IOI) open infrastructure selection tool, Infra Finder (https ...
Lippincott, Sarah   +3 more
core   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Infrastructures : Time to Invest

open access: yes, 2008
Influential policy advisors call for a reform of the management of, and investment in infrastructures at both the regional and the national level.
openaire   +3 more sources

10 year infrastructure plan : 2018-2027

open access: yes, 2018
Strategic infrastructure investment is a key enabler of economic development and the future growth of the Northern Territory. Well planned and strategically timed infrastructure projects contribute to creating jobs, improved services and attract people ...

core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

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