Results 51 to 60 of about 848,920 (295)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Code, space and everyday life [PDF]

, 2004
In this paper we examine the role of code (software) in the spatial formation of collective life. Taking the view that human life and coded technology are folded into one another, we theorise space as ontogenesis.
Dodge, Martin, Kitchin, Rob
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Advanced Techniques for IaC: Enhancing Automation and Optimization in Cloud-Based Infrastructure Management

Proceedings of the International Conference on Applied Innovations in IT
In the modern IT environment, Infrastructure as Code (IaC) has revolutionized the management of cloud-based infrastructure by automating the deployment and configuration of resources.
Liliia Bodnar, Mykola Bodnar, Kateryna Shulakova, Oksana Vasylenko, Eduard Siemens, Roman Tsarov, Olha Yavorska, Olena Tyurikova   +7 more
doaj   +1 more source

Introducing Energy Efficiency into SQALE [PDF]

, 2013
Energy Efficiency is becoming a key factor in software development, given the sharp growth of IT systems and their impact on worldwide energy consumption.
Ardito, Luca, Morisio, Maurizio, Procaccianti, Giuseppe, Vetro', Antonio   +3 more
core  

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Intent-Based Infrastructure and Service Orchestration Using Agentic-AI

IEEE Open Journal of the Communications Society
This paper introduces a novel framework that integrates agentic Artificial Intelligence (AI) with Intent-Based Networks (IBN) to enable autonomous management, configuration, and optimization of mobile network services and resources.
Dimitrios Brodimas, Alexios Birbas, Dimitrios Kapolos, Spyros Denazis   +3 more
doaj   +1 more source

A Toolkit For Storage Qos Provisioning For Data-Intensive Applications

Computer Science, 2012
This paper describes a programming toolkit developed in the PL-Grid project, named QStorMan, which supports storage QoS provisioning for data-intensive applications in distributed environments. QStorMan exploits knowledge-oriented methods for matching
Renata Słota, Dariusz Krol, Kornel Skałkowski, Michal Orzechowski, Darin Nikolow, Bartosz Kryza, Michal Wrzeszcz, Jacek Kitowski   +7 more
doaj   +1 more source

GiRaFFE: An Open-Source General Relativistic Force-Free Electrodynamics Code

, 2017
We present GiRaFFE, the first open-source general relativistic force-free electrodynamics (GRFFE) code for dynamical, numerical-relativity generated spacetimes.
Babiuc, Maria C., Choudhary, Ashok, Etienne, Zachariah B., McWilliams, Sean T., Wan, Mew-Bing   +4 more
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source