Results 61 to 70 of about 268,495 (267)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Landslide Hazard and Rainfall Threshold Assessment: Incorporating Shallow and Deep-Seated Failure Mechanisms with Physics-Based Models

Geosciences
Landslides pose a significant threat worldwide, leading to numerous fatalities and severe economic losses. The city of Manizales, located in the Colombian Andes, is particularly vulnerable due to its steep topography and permeable volcanic ash-derived ...
Roberto J. Marin, Julián Camilo Marín-Sánchez, Johan Estiben Mira, Edwin F. García, Binru Zhao, Jeannette Zambrano   +5 more
doaj   +1 more source

Public assessment of green infrastructure benefits and associated influencing factors in two Ethiopian cities: Bahir Dar and Hawassa

BMC Ecology, 2019
Background Currently, urban green infrastructure is increasingly gaining attention as a source of multiple benefits. Understanding how city residents perceive the benefits of green infrastructure is critical for urban policy and planning.
Kassahun Gashu, Tegegne Gebre-Egziabher
doaj   +1 more source

Assessment of infrastructure of forest land

IOP Conference Series: Materials Science and Engineering, 2020
Abstract The article discusses the main directions of forest policy in the field of creating forest fund infrastructure, provides foreign experience in accounting for infrastructure and comparative indicators. An analysis of the transport infrastructure of the forest fund was carried out, as well as a methodology for assessing the ...
V Kovyazin, A Romanchikov, A Kitcenko
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Probabilistic Assessment of Civil Infrastructure Resilience to Earthquakes

Computer-Aided Civil and Infrastructure Engineering, 2015
The large losses occurred in the past due to earthquakes, even in highly developed countries, as well as the ensuing prolonged inactivity of the stricken societies, imparted momentum to research into regional seismic impact and community resilience to earthquakes.
FRANCHIN, Paolo, CAVALIERI, FRANCESCO
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Land Suitability Assessment of Green Infrastructure Development

TeMA: Journal of Land Use, Mobility and Environment, 2019
Urban green space, an integral part of urban ecosystems, provides important environmental and social services that mitigate environmental problems caused by rapid urbanisation and urban sprawl.
Eda Ustaoglu, Arif Cagdas Aydınoglu
doaj   +1 more source