Results 51 to 60 of about 1,061,537 (308)
A Systems-Based Approach to the Identification of User/Infrastructure Interdependencies as a Precursor to Identifying Opportunities to Improve Infrastructure Project Value/Cost Ratios [PDF]
, 2015 The bulk of the investment needed for infrastructure renewal in the United Kingdom will have to come from private sector investors, who will require attractive value/cost ratios.
Baker, C. +5 more
core
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
The Coherence Problem: Mapping the Theory and Delivery of Infrastructure Resilience Across Concept, Form, Function, and Experienced Value [PDF]
, 2015 In this contribution we explore the interface between the functional characteristics of infrastructures as artefacts and social need supplier. Specifically we are concerned with the ways in which infrastructure performance measures are articulated and ...
Jeffrey, P., Smith, H.
core
Protein folding and the robustness of cells
, 2007 The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of molecules it will bind to.
Revilla, Ferran D. +2 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Scientific ReportsLand use patterns and anthropogenic activities exert diverse impacts on river water quality and ecosystem health across spatial and temporal scales. Under ongoing pressures from human activities and climate change, it is urgently needed to understand the
Xiaojing Zhang +4 more
doaj +1 more source
I-11: Sustainable Supercorridor [PDF]
, 2015 Recently enacted Federal transportation legislation known as MAP-21 — Moving Ahead for Progress in the 21st Century — has brought renewed attention to a proposed interstate corridor connecting Las Vegas, Phoenix and Tucson, Arizona.
Samuels, L.C.
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
BuildingsIn this paper, a novel T-shaped steel–concrete composite shear wall (TSCCW) is proposed. Low-cycle reciprocating tests were carried out on the TSCCW to investigate its performance in terms of its damage characteristics, hysteretic properties, energy ...
Xuan Mo +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source