Results 91 to 100 of about 217,401 (313)

Money as Infrastructure

open access: yesSSRN Electronic Journal, 2017
Traditional infrastructure regulation–the law of regulated industries–rests atop three pillars: rate regulation, entry restriction, and universal service. This mode of regulation has typically been applied to providers of network-type resources: resources that are optimally supplied as integrated systems.
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

An Investigation of Historic Transportation Infrastructure Preservation and Improvement through Historic Building Information Modeling

open access: yesInfrastructures
Historical transportation infrastructures (HTIs) like railways and bridges are essential to our cultural heritage. However, the preservation and enhancement of these structures pose significant challenges due to their complex nature and the need for ...
Rnin Salah   +3 more
doaj   +1 more source

DyVOSE project: experiences in applying privilege management infrastructures [PDF]

open access: yes, 2006
Privilege Management Infrastructures (PMI) are emerging as a necessary alternative to authorization through Access Control Lists (ACL) as the need for finer grained security on the Grid increases in numerous domains. The 2-year JISC funded DyVOSE Project
Koetsier, J.   +5 more
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Internationalization of Infrastructures: Proceedings of the 12th Annual International Conference on the Economics of Infrastructures

open access: yes, 2009
What are the economic effects of the internationalization of infrastructures? We have addressed this question at the 12th Annual International Conference on the Economics of Infrastructures (Delft, May 2009).
Auger, J.F.   +5 more
core  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

New Challenges in Critical Infrastructures : A US Perspective [PDF]

open access: yes
L'émergence d'un plus large spectre de vulnérabilités (terrorisme, sabotage, conflits locaux et catastrophes naturelles) et l'interdépendance croissante de l'activité économique rendent particulièrement vulnérables les grands réseaux vitaux des pays ...
Erwann Michel-Kerjan
core  

Development of grid frameworks for clinical trials and epidemiological studies [PDF]

open access: yes, 2006
E-Health initiatives such as electronic clinical trials and epidemiological studies require access to and usage of a range of both clinical and other data sets. Such data sets are typically only available over many heterogeneous domains where a plethora
Ajayi, Oluwafemi   +5 more
core  

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