Results 61 to 70 of about 217,401 (313)
Infrastructural surveillance [PDF]
New Media & Society, 2019 This article proposes a new model of privacy: infrastructural surveillance. It departs from Agre’s classic distinction between surveillance and capture by examining the sociotechnical claims of connected and autonomous vehicles (CAVs) as requiring totalising surveillance of passengers and environment in order to operate.
Alex Gekker, Sam Hind
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
04201 Summary – Content Distribution Infrastructures [PDF]
, 2006 We provide a summary of the Dagstuhl workshop on content distribution infrastructures. The presentations and group discussions of the workshop are summarized in context, and visionary and outrageous opinions of the workshop participants are ...
Plagemann, Thomas Peter +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2022 Este proyecto está cofinanciado por el Ministerio español de Universidades en el marco del Plan de Recuperación, Transformación y Resiliencia, por la Unión Europea – NextGenerationEU, y por la Universidad de Valladolid.
Gastaldi, Francesco, Camerin, Federico
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Infrastructured Timescapes of the Anthropocene and Climate Change
TecnoscienzaThis introduction aims to frame the main contents of the special issue and offers an overview of the collected contributions. It discusses key conceptual themes and reflects on how an infrastructural and temporal approach can open new understandings of ...
Claudio Coletta
doaj +1 more source
Migration Infrastructure [PDF]
International Migration Review, 2014 Based on the authors’ long-term field research on low-skilled labor migration from China and Indonesia, this article establishes that more than ever labor migration is intensively mediated. Migration infrastructure – the systematically interlinked technologies, institutions, and actors that facilitate and condition mobility – serves as a concept to ...
Xiang, B., Lindquist, J.
openaire +3 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source