Results 201 to 210 of about 1,616,867 (388)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Lecanemab over a two-year duration: Key insights from a regional specialty medical center. [PDF]

J Prev Alzheimers Dis
Shields LBE, Hannah H, Cooper GE, Kluthe T, Hart RN, Thaliath AP, Dennis BC, Freeman SW, Cain JF, Shang WY, Wasz KM, Orr AT, Shields CB, Barve SS, Pugh KG.   +14 more
europepmc   +1 more source

Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting.

Journal of Thoracic and Cardiovascular Surgery, 2003
A. Furnary, Guangqiang Gao, G. Grunkemeier, Yingxing Wu, Kathryn J. Zerr, Stephen O. Bookin, H. Floten, A. Starr   +7 more
semanticscholar   +1 more source

The influence of bicarbonate infusion system on ionized calcium concentration: a study on the difference among the methods

, 1981
Takashi Shibamoto, Masahiro Taniguchi, Seinosuke Nakagawa, Tomiya Abe   +3 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Time of Day Drives Angiotensin II-Dependent Hypertension. [PDF]

Hypertension
Benson LN, Hyndman KA, Pollock DM, Pollock JS.   +3 more
europepmc   +1 more source

INFUSION THROMBOPHLEBITIS

British Journal of Anaesthesia, 1986
L W, Gemmell, D R, Donaldson, C J, Smith
openaire   +2 more sources

A study on green practice infusion of the SMES in the context of circular economy

Yi‐Hui Ho, Cheng‐Kun Wang, Syed Shah Alam, Chieh‐Yu Lin   +3 more
openalex   +2 more sources

Postoperative hepatic arterial infusion pump chemotherapy after resection of multinodular colorectal liver metastases [PDF]

Romane Brawermann, Ali Bohlok, Desislava Germanova, Vincent Donckier, Jean‐Luc Van Laethem, F. Tannouri, Gontran Verset, Valério Lucidi   +7 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source